Physician-guided
Every prescription is written by a NY-licensed clinician, not an algorithm or survey.
From $118Manhattan onlyPrescription skincare,
Prescription skincare,
re-imagined.
A NY-licensed clinician reviews your intake. If treatment is prescribed, a licensed pharmacy compounds your formula and a Thryvera courier delivers it to your Manhattan door.
NY-licensed cliniciansOnly charged if approvedLocal Manhattan delivery
Manhattan only — for nowWe don’t ship.
We don’t ship.
We deliver.
Every prescription is hand-delivered in Manhattan after clinical approval and pharmacy preparation. No warehouses. No carriers. No rerouted boxes.
Free delivery on every orderDiscreet, hand-delivered to your door
FounderA note from our founder
I started Thryvera after watching too many people move between rushed visits and generic product advice. Skin is more personal than that. Care should be too.
Sameet AhmedFounder & CEO
How It Works
Four steps. One face.
You write it. A clinician reads it. A pharmacist prepares it. A local courier delivers it.
Medical intake
Share face photos, skin history, allergies, your current routine, and prior prescriptions for clinician review. Identity verification ensures that any prescription carries your legal name.
Clinical review
A NY-licensed clinician reviews your intake, asks follow-ups if needed, and writes a personalized prescription.
Compounded for you
A licensed compounding pharmacy mixes your formula by hand during the week it is prescribed, using the ingredients and strengths selected by your clinician.
Delivered & supported
Hand-delivered to your Manhattan door after dispensing. Message your care team anytime.
Why Thryvera
The middle road between shelf care and a separate office visit.
Prescription active ingredients
A licensed pharmacy compounds each formula at the strengths selected by the prescriber.
One face per formula
The collection includes five evening formulas and five AM + PM duos. Your clinician selects a formula based on your intake, concern, and tolerance.
Manhattan hand-delivery
Local courier delivery in Manhattan after your clinician approves your prescription and the pharmacy prepares it.
PM Formulas
Five evening prescriptions
AM + PM Duos
Five complete rituals
Inside the formulas
Prescription actives, selected for your skin.
Every Thryvera formula begins with a prescription tretinoin backbone. Your clinician may layer in additional actives based on your intake, skin goals, and tolerance.
Tretinoin0.025%
Cell turnoverA prescription retinoid used in acne care and some photoaging regimens. Your clinician decides whether it is appropriate for your skin.
Niacinamide4%
Barrier · oil controlA vitamin B3 derivative commonly used to support skin-barrier comfort and tolerability in multi-active formulas.
Azelaic Acid10–15%
Tone · rosaceaA topical acid your clinician may select for acne, rosacea-prone skin, or pigment concerns when clinically appropriate.
Hydroquinone4%
Pigment correctionA prescription skin-lightening ingredient that may be selected for melasma or post-inflammatory hyperpigmentation when clinically appropriate.
4-month maximum · 2-month break requiredTranexamic Acid3%
Pigment · rednessAn ingredient sometimes used in pigment-focused regimens; selected only when your clinician considers it appropriate.
Peptide Complex1%
FirmnessA supportive cosmetic ingredient used for skin feel and appearance. It is not the prescription driver in the formula.
Compounded medications are not FDA-approved. Each formula is personalized by your licensed prescriber based on your medical intake.
The ritual
Two minutes, twice a day. That’s it.
Morning ritual
- 1Wash with a gentle cleanser
- 2Apply your AM formula (duo only)
- 3Moisturize, then SPF 30+
Evening ritual
- 1Wash with a gentle cleanser
- 2Pat fully dry
- 3Apply a pea-sized amount of your PM formula
- 4Moisturize over the top
Begin three nights a week, increase as tolerated. Your clinician will adjust your cadence at any check-in.
How it stacks up
What you get for $118 that you won’t get anywhere else.
| Thryvera | Shelf routine | Office visit | Subscription skincare | |
|---|---|---|---|---|
| Prescription-strength actives | Yes | — | Yes | Yes |
| Personalized to your intake | Per-patient compounded | — | Yes, after visit | — |
| Path to your formula | Intake, review, compounding, courier | Self-selected products | Separate visit and fill | Standardized subscription |
| 60-day Thryvera plan | $118–$158 | — | — | — |
| Formula adjustment review | When clinically appropriate | — | New visit · new co-pay | — |
| Manhattan local-courier delivery | Yes | Walk in, walk out | — | — |
Comparison is based on care-model differences, not competitor pricing claims. Individual treatment fit is determined by the reviewing clinician.
What is included
One price. Everything covered.
Your first 60-day treatment includes the clinical consultation, so there is no separate visit fee. Your card is authorized for the plan total at intake; if care isn’t approved, the authorization is released.
From$118/ 60 days
The simplest version of Thryvera. One prescription, every night.
Included- 60-day supply, milligram-precise
- Initial intake & clinical review
- Unlimited messaging with your clinician
- Formula adjustment review when clinically appropriate
- Local Manhattan hand-delivery
Refills $118 every 60 days. Pause or cancel future cycles from your account.
From$158/ 60 days
The full version. Pigment and texture, breakouts and barrier. Two formulas, one routine.
Included- 60-day supply, milligram-precise
- Initial intake & clinical review
- Unlimited messaging with your clinician
- Formula adjustment review when clinically appropriate
- Local Manhattan hand-delivery
Refills $158 every 60 days. Pause or cancel future cycles from your account.
You’re only charged if approved.
Submit your intake free of charge. Your card is held for the plan total when you finalize your order; if your clinician determines Thryvera isn’t right for you, the hold is released in full and you’ll receive suggested next steps.
In their words
How it has felt to be heard.
Patient experience reflections, shared with permission. Individual experiences may vary; testimonials do not constitute medical claims.
The first thing my clinician asked was how I felt about my skin, not what I’d already tried. That single question is everything I’ve ever wanted from a derm visit and never gotten.
MK
Maryam K.Defense PM client
The pharmacy jar shows up with my name on the label and my clinician’s. It feels like medicine, not marketing.
NP
Nikita P.Glow PM client
I messaged at 9pm about a tingle. Got a real reply, from a real clinician, before bed. I’ve never had that kind of access.
AK
Andy K.Radiance PM client
What to expect
A realistic timeline, set by your clinician.
Prescription skincare works on biology, not marketing cycles. The timeline below is a general guide. Your clinician will set expectations for your skin.
Adjust
Mild dryness, flaking, or transient breakouts may occur as your skin acclimates. Message your clinician if symptoms are painful or concerning.
Texture
At this stage, your clinician may assess changes in texture, breakouts, and irritation. Timing varies by formula and response.
Pigment
Changes in tone can take months to assess. Your clinician will set expectations for post-acne marks, melasma, and sun damage.
Individual results vary. Your clinician sets your expectations during the consult and may adjust your formula at any check-in.
Your care teamA real clinician. Licensed
A real clinician. Licensed
in New York.
Every Thryvera prescription is written by a NY-licensed clinician. Follow-ups, formula changes, and clinical messages are reviewed through the MD Integrations clinical network.
- Who writes it
A NY-licensed clinician reviews your intake and decides whether to prescribe.
- Who replies
Clinical follow-ups and medication questions are reviewed by the MD Integrations care team assigned to your case.
- How it works
Care is delivered through the MD Integrations clinical network. Every prescription is reviewed against your intake before M&S Drugs Inc. d/b/a Thryvera compounds and delivers it.
Questions, answered
Common questions.
Yes. Every Thryvera formula is a compounded prescription medication written by a NY-licensed clinician and dispensed by a licensed compounding pharmacy. Compounded medications are not FDA-approved as a class. Your clinician is responsible for the personalized formulation.
Over-the-counter retinols are cosmetic products. Thryvera formulas may include prescription tretinoin and other clinician-selected actives when appropriate for your skin, tolerance, and treatment goals.
Your card is tokenized at intake and a temporary authorization for the full first 60-day total is placed when you submit your review. Nothing is charged until your clinician approves the prescription, at which point the authorization captures as your first treatment and delivery. If your clinician decides Thryvera isn’t right for you, the authorization is released in full.
No. Your clinical consultation is included in your plan total. If your clinician can’t approve care, the entire authorization, including the plan total, is released and nothing settles to your card.
Refills are billed automatically every 60 days at the price shown on your plan card. Mono refills are $118 and Duo refills are $158, depending on actives. You’ll receive an email seven days before each refill is prepared. Pause, skip, or cancel anytime from your account before compounding starts.
If your formula is not a good fit after a fair trial, your clinician can review your case for a no-cost reformulation when clinically appropriate. Compounded prescriptions can’t be returned for a refund once prepared, but support can help route concerns to the right team.
Response timing varies by person, condition, formula, and adherence. Your clinician will set realistic expectations during your initial consultation and can adjust treatment if your skin is not tolerating it.
Message your clinician right away. If a reformulation is needed, it’s free. We expect a normal adjustment period; we don’t expect you to suffer through it alone.
After clinical approval and pharmacy preparation, Thryvera routes Manhattan orders by local courier. Delivery updates appear in your portal when available. Thryvera is currently Manhattan only; we do not ship outside the borough.
Yes. There’s no subscription lock-in or cancellation fee. You can pause for a season, skip a refill, or stop entirely from your account. Your medical records and active prescription remain available on your dashboard.
No. Tretinoin and hydroquinone are contraindicated during pregnancy and breastfeeding. Your intake will flag this; your clinician will not write a prescription if you’re pregnant, nursing, or actively trying to conceive.
Both contain hydroquinone 4%, which carries a risk of ochronosis with prolonged continuous use. Thryvera requires a 4-month-on / 2-month-off cycle for these formulas as a clinical safety rule.
Compounded medications are typically not covered by insurance. Thryvera’s price includes the visit, with no separate fee or co-pay. Support can provide a superbill for you to submit for possible HSA / FSA reimbursement.
Begin your formulaReady to transform
Ready to transform
your skin?
Complete your medical intake for clinician review. If care is approved, a licensed pharmacy will compound your formula. We place a temporary hold for your plan total at intake; if care isn’t approved, the hold is released in full.
Card required · temporary hold, captured if your clinician approves